Open AccessInterim estimates of the effectiveness of influenza vaccination against influenza‐associated hospitalization in children in Hong Kong, 2015–16
Author(s) -
Cowling Benjamin J.,
Kwan Mike Y. W.,
Wong Joshua S. C.,
Feng Shuo,
Leung ChiWai,
Chan Eunice L. Y.,
Chan KwokHung,
Ng TakKeung,
To WingKin,
Peiris Malik J. S.,
Chiu Susan S.
Publication year - 2017
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12399
Subject(s) - medicine , vaccination , confidence interval , logistic regression , interim , pediatrics , conditional logistic regression , influenza vaccine , emergency medicine , immunology , archaeology , history
From 1 September 2015 through 31 January 2016, we enrolled 2068 children 6 months to 17 years of age admitted to hospital with a febrile acute respiratory infection in our test‐negative study. Information on receipt of 2015–16 northern hemisphere inactivated influenza vaccination was elicited from parents or legal guardians. Using conditional logistic regression adjusting for age and matching on calendar time, we estimated influenza vaccine effectiveness against hospitalization with influenza A or B to be 79.2% (95% confidence interval: 42.0%–92.4%). Annual influenza vaccination should be more widely used in children in Hong Kong.