Open AccessGenetic characterisation of influenza C viruses detected in Singapore in 2006
Author(s) -
Ting Peijun,
Seah Shirley GekKheng,
Lim Elizabeth AiSim,
Liaw Jasper ChinWen,
BoonHuan Tan
Publication year - 2016
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12352
Subject(s) - phylogenetic tree , biology , hemagglutinin (influenza) , lineage (genetic) , virology , genome , gene , virus , phylogenetics , genetics
In an earlier study on respiratory infections in Singapore military recruits, four influenza C virus ( FLUCV ) infections were detected out of the 1354 samples collected. All four isolates were detected in 2006, and their whole genome was completely sequenced and analysed. Phylogenetic analysis of the hemagglutinin esterase fusion ( HEF ) gene revealed that all four Singapore isolates belonged to the C/Japan‐Kanagawa/1/76‐related lineage. However, the genes of the four FLUCV isolates had origins from several different lineages, and the genome composition resembles that of the C/Japan‐Miyagi/9/96‐like strains that had been circulating in Japan between 1996 and 2000.