Open AccessGenomic analyses detect Eurasian‐lineage H10 and additional H14 influenza A viruses recovered from waterfowl in the Central United States
Author(s) -
Fries Anthony C.,
Nolting Jacqueline M.,
Bowman Andrew S.,
Killian Mary L.,
Wentworth David E.,
Slemons Richard D.
Publication year - 2014
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12250
Subject(s) - subtyping , biology , virology , reassortment , influenza a virus , waterfowl , genetics , genetic diversity , lineage (genetic) , evolutionary biology , zoology , virus , gene , covid-19 , population , infectious disease (medical specialty) , medicine , ecology , disease , environmental health , pathology , habitat , computer science , programming language
The accurate and timely characterization of influenza A viruses ( IAV ) from natural reservoirs is essential for responses to animal and public health threats. Differences between antigenic and genetic subtyping results for 161 IAV isolates recovered from migratory birds in the central United States during 2010–2011 delayed the recognition of four isolates of interest. Genomic sequencing identified the first reported Eurasian‐origin H10 subtype in North America and three additional H14 isolates showing divergence from previously reported H14 isolates. Genomic analyses revealed additional diversity among IAV isolates not detected by antigenic subtyping and provided further insight into interhemispheric spread of avian‐origin IAV s.