Open AccessDetection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes
Author(s) -
Imamura Tadatsugu,
Suzuki Akira,
Lupisan Socorro,
Kamigaki Taro,
Okamoto Michiko,
Roy Chandra Nath,
Olveda Remigio,
Oshitani Hitoshi
Publication year - 2014
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12206
Subject(s) - medicine , pneumonia , enterovirus , enterovirus infections , intensive care medicine , pediatrics , virology , virus
Enterovirus 68 ( EV 68) infection occasionally manifests with fatal outcomes. However, detection of EV 68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for EV 68. Of total 28 nasopharyngeal sample‐positive patients, EV 68 was detected in serum samples among 12 (43%) patients aged between 1 and 4 years. Our results suggest that EV 68 can cause viremia by which the virus may exhibit systemic manifestations.