Open AccessExcess mortality impact of two epidemics of pandemic influenza A ( H 1 N 1pdm09) virus in H ong K ong
Author(s) -
Wu Peng,
Goldstein Edward,
Ho LaiMing,
Wu Joseph T.,
Tsang Thomas,
Leung Gabriel M.,
Cowling Benjamin J.
Publication year - 2014
Publication title -
influenza and other respiratory viruses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.743
H-Index - 57
eISSN - 1750-2659
pISSN - 1750-2640
DOI - 10.1111/irv.12196
Subject(s) - excess mortality , pandemic , confidence interval , demography , population , medicine , influenza pandemic , covid-19 , human mortality from h5n1 , virology , environmental health , disease , infectious disease (medical specialty) , sociology
H ong K ong experienced two large epidemics of pandemic influenza A ( H 1 N 1pdm09). We used regression methods to estimate the excess mortality associated with each epidemic. The first epidemic of H 1 N 1pdm09 peaked in S eptember 2009 and was associated with 2·13 [95% confidence interval ( CI ): −8·08, 11·82] excess all‐cause deaths per 100 000 population. The second epidemic of H 1 N 1pdm09 in early 2011 was associated with 4·72 [95% CI : −0·70, 10·50] excess deaths per 100 000 population. More than half of the estimated excess all‐cause deaths were attributable to respiratory causes in each epidemic. The reasons for substantial impact in the second wave remain to be clarified.