Bat cells from   P teropus alecto  are susceptible to influenza  A  virus infection and reassortment | Zendy

Dlugolenski Daniel | Zendy; Jones Les | Zendy; Tompkins S. Mark | Zendy; Crameri Gary | Zendy; Wang LinFa | Zendy; Tripp Ralph A. | Zendy

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Bat cells from P teropus alecto are susceptible to influenza A virus infection and reassortment

Author(s) -

Dlugolenski Daniel,

Jones Les,

Tompkins S. Mark,

Crameri Gary,

Wang LinFa,

Tripp Ralph A.

Publication year - 2013

Publication title -

influenza and other respiratory viruses

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.743

H-Index - 57

eISSN - 1750-2659

pISSN - 1750-2640

DOI - 10.1111/irv.12128

Subject(s) - reassortment , biology , influenza a virus , virology , waterfowl , virus , viral replication , microbiology and biotechnology , covid-19 , infectious disease (medical specialty) , ecology , disease , pathology , habitat , medicine

Waterfowl are primary hosts for influenza A viruses ( IAV s); however, there is sporadic infection of swine and other species that pose a risk of zoonotic spread. Yellow‐shouldered bats were shown to be hosts of an IAV , thereby constituting a potential novel reservoir. We show that P teropus alecto kidney cells ( P a K i) are susceptible to infection and sustain replication of A / WSN /33 ( H 1 N 1) and A / V ietnam/1203/04 ( H 5 N 1). Importantly, we show that co‐infection of P a K i cells results in novel reassortants.

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