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Salivary pH and colonization by oral Candida in children and adolescents submitted to haemodialysis
Author(s) -
Andrade Marcia Rejane Thomas Canabarro,
Curvelo José Alexandre da Rocha,
Moraes Daniel Clemente,
Portela Maristela,
FerreiraPereira Antonio,
Soares Rosangela Maria de Araújo,
Primo Laura Guimarães
Publication year - 2018
Publication title -
international journal of paediatric dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.183
H-Index - 62
eISSN - 1365-263X
pISSN - 0960-7439
DOI - 10.1111/ipd.12403
Subject(s) - saliva , medicine , candida parapsilosis , colonization , candida albicans , gastroenterology , microbiology and biotechnology , antifungal , biology , dermatology
Background Fungal infections are a serious problem among haemodialysis patients. Aim The aims of this study were to estimate the frequency of oral Candida species among children and adolescents undergoing haemodialysis ( HD ), to identify the isolated species, and to study the relationship between haemodialysis duration, amounts of colony‐forming units, and salivary pH . Design A matched sample of 52 patients undergoing HD and 52 healthy individuals were selected. The samples were obtained from the dorsum of the tongue, and the colonies were identified through a substrate assimilation test. Stimulated whole saliva was collected from each patient for evaluation of salivary pH . Results The frequency of oral Candida species was 34.6% (18/52) and 46.20% (24/52) in the HD and control groups ( P = 0.23), respectively. Candida parapsilosis complex was the most frequently isolated fungi species in the HD group ( P = 0.03). A HD therapy duration of more than 1 year was statistically correlated with a higher number of colony‐forming units ( P = 0.03) but was not statistically related to salivary pH . Conclusions Candida parapsilosis complex was the most frequently isolated fungal species in the young HD patients, and the duration therapy was associated with higher oral colonization.