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Influence of salivary parameters in the caries development in orthodontic patients—an observational clinical study
Author(s) -
Cardoso Andréia A.,
Lopes Lenita M.,
Rodrigues Lívia P.,
Teixeira Jéssica J.,
SteinerOliveira Carolina,
NobredosSantos Marinês
Publication year - 2017
Publication title -
international journal of paediatric dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.183
H-Index - 62
eISSN - 1365-263X
pISSN - 0960-7439
DOI - 10.1111/ipd.12295
Subject(s) - medicine , saliva , dentistry , oral hygiene , amylase , positive correlation , negative correlation , gastroenterology , biochemistry , chemistry , enzyme
Background Previous studies have shown during the orthodontic treatment, the prevalence of active caries lesions ( ACL ) in 30 to 70% of patients. Aim To evaluate the effect of orthodontic treatment on salivary properties considering caries development. Design Twenty two individuals (11–22 years) were assessed regarding caries, oral hygiene, sugar exposure, salivary flow rate ( SFR ), buffering capacity, pH , carbonic anhydrase VI ( CA VI ) and amylase activity, at baseline, 1, 3 and 6 months after the orthodontic appliances placement. Caries index was determined by Nyvad criteria. CA VI and amylase activities were performed by zymography and ELISA , respectively. Results Buffering capacity decreased after 3 months ( P < 0.0001) and showed positive correlation with pH at baseline and after 1 month in individuals who did not develop active caries lesions. Amylase activity decreased after 1 and 6 months ( P = 0.0003) and presented positive correlation with CA VI in patients who developed ACL . SFR increased after 1 month ( P = 0.0283) and showed positive correlation with CA VI activity after 3 months in individuals who did not develop ACL . Salivary pH showed negative correlation with CA VI after 1 month in patients who did not develop ACL . ACL were firstly diagnosed after 3 months. Conclusions The present study demonstrated that saliva of individuals under orthodontic treatment is subjected to changes in properties that have implications on the onset of ACL .