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Different health effects of indoor‐ and outdoor‐originated PM 2.5 on cardiopulmonary function in COPD patients and healthy elderly adults
Author(s) -
Chi Rui,
Chen Chen,
Li Hongyu,
Pan Lu,
Zhao Bin,
Deng Furong,
Guo Xinbiao
Publication year - 2019
Publication title -
indoor air
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.387
H-Index - 99
eISSN - 1600-0668
pISSN - 0905-6947
DOI - 10.1111/ina.12521
Subject(s) - copd , medicine , environmental health , lung function , indoor air , gerontology , environmental science , emergency medicine , environmental engineering , lung
Numerous research has explored the associations of outdoor or indoor fine particulate matter (PM 2.5 ) and health effects; however, few studies compared the effects of indoor PM 2.5 originated from outdoor (PM 2.5,os ) and indoor sources (PM 2.5,is ). To assess the associations of PM 2.5,os and PM 2.5,is with cardiopulmonary function in patients with chronic obstructive pulmonary disease (COPD) and healthy elderly adults, blood pressure (BP) and pulmonary function were repeatedly examined in 43 COPD patients and their 32 healthy spouses in Beijing, China. Iron was used as tracer element to separate PM 2.5,os and PM 2.5,is . Mixed‐effects models were applied to assess the associations of PM 2.5,os or PM 2.5,is and health effects after controlling for potential confounders. There was a reduction in forced expiratory volume in first second (FEV 1 ) in COPD patients associated with PM 2.5,is during the heating season. PM 2.5,os was positively associated with diastolic BP (DBP) in healthy elderly adults during the heating season. There was a reduction in peak expiratory flow (PEF) in healthy elderly adults associated with PM 2.5,os during the non‐heating season. Exposure to indoor‐ and outdoor‐originated PM 2.5 had different health effects on cardiopulmonary function in different populations. The results provide supporting evidence for improving indoor air quality to promote public health among susceptible population.