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Accumulation of gas‐phase methamphetamine on clothing, toy fabrics, and skin oil
Author(s) -
Morrison G.,
Shakila N. V.,
Parker K.
Publication year - 2015
Publication title -
indoor air
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.387
H-Index - 99
eISSN - 1600-0668
pISSN - 0905-6947
DOI - 10.1111/ina.12159
Subject(s) - methamphetamine , chemistry , clothing , environmental science , chromatography , toxicology , zoology , environmental chemistry , medicine , pharmacology , biology , archaeology , history
Abstract To better understand methamphetamine exposure and risk for occupants of former residential clandestine methamphetamine laboratories, we measured the dynamic accumulation of methamphetamine in skin oil, cotton and polyester ( PE ) clothing, upholstery, and toy fabric (substrates) exposed to 15–30 ppb (91–183 μ g/m 3 ) neutral methamphetamine in air for up to 60 days. The average equilibrium partition coefficients at 30% RH , in units of μ g of methamphetamine per gram of substrate per ppb, are 3.0 ± 0.2 for a PE baby blanket, 5.6 ± 3.5 for a PE fabric toy, 3.7 ± 0.2 for a PE shirt, 18.3 ± 8.0 for a PE /cotton upholstery fabric, and 1200 ± 570 in skin oil. The partition coefficients at 60% RH are 4.5 ± 0.4, 5.2 ± 2.1, 4.5 ± 0.6, 36.1 ± 3.6, and 1600 ± 1100 μ g/(g ppb), respectively. There was no difference in the partition coefficient for a clean and skin‐oil‐soiled cotton shirt [15.3 ± 2.1 μ g/(g ppb) @ 42 days]. Partition coefficients for skin oil may be sensitive to composition. ‘Mouthing’ of cloth is predicted to be the dominant exposure pathway [60 μ g/(kg body weight*ppb)] for a toddler in former meth lab, and indoor air concentrations would have to be very low (0.001 ppb) to meet the recommended reference dose for children.