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B regulatory cells in allergy
Author(s) -
Ma Siyuan,
Satitsuksanoa Pattraporn,
Jansen Kirstin,
Cevhertas Lacin,
Veen Willem,
Akdis Mübeccel
Publication year - 2021
Publication title -
immunological reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.839
H-Index - 223
eISSN - 1600-065X
pISSN - 0105-2896
DOI - 10.1111/imr.12937
Subject(s) - regulatory b cells , immunology , biology , allergy , inflammation , antibody , b cell
B cells have classically been recognized for their unique and indispensable role in the production of antibodies. Their potential as immunoregulatory cells with anti‐inflammatory functions has received increasing attention during the last two decades. Herein, we highlight pioneering studies in the field of regulatory B cell (Breg) research. We will review the literature on Bregs with a particular focus on their role in the regulation of allergic inflammation.