z-logo
Premium
Spatial and temporal coordination of antiviral responses by group 1 ILC s
Author(s) -
Adams Nicholas M.,
Sun Joseph C.
Publication year - 2018
Publication title -
immunological reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.839
H-Index - 223
eISSN - 1600-065X
pISSN - 0105-2896
DOI - 10.1111/imr.12710
Subject(s) - biology , context (archaeology) , innate immune system , population , immunology , viral infection , immunity , microbiology and biotechnology , virology , immune system , virus , paleontology , demography , sociology
Summary Group 1 innate lymphocytes consist of a phenotypically, spatially, and functionally heterogeneous population of NK cells and ILC 1s that are engaged during pathogen invasion. We are only beginning to understand the context‐dependent roles that different subsets of group 1 innate lymphocytes play during homeostatic perturbations. With a focus on viral infection, this review highlights the organization and regulation of spatially and temporally distinct waves of NK cell and ILC 1 responses that collectively serve to achieve optimal viral control.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom