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The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology
Author(s) -
Harding Simon D.,
Faccenda Elena,
Southan Christopher,
Pawson Adam J.,
Maffia Pasquale,
Alexander Stephen P. H.,
Davenport Anthony P.,
Fabbro Doriano,
LeviSchaffer Francesca,
Spedding Michael,
Davies Jamie A.
Publication year - 2020
Publication title -
immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.297
H-Index - 133
eISSN - 1365-2567
pISSN - 0019-2805
DOI - 10.1111/imm.13175
Subject(s) - immunopharmacology , clinical pharmacology , pharmacology , resource (disambiguation) , medicine , context (archaeology) , immune system , action (physics) , immunology , computer science , biology , computer network , paleontology , physics , quantum mechanics
Summary Given the critical role that the immune system plays in a multitude of diseases, having a clear understanding of the pharmacology of the immune system is crucial to new drug discovery and development. Here we describe the International Union of Basic and Clinical Pharmacology (IUPHAR) Guide to Immunopharmacology (GtoImmuPdb), which connects expert‐curated pharmacology with key immunological concepts and aims to put pharmacological data into the hands of immunologists. In the pursuit of new therapeutics, pharmacological databases are a vital resource to researchers through providing accurate information on the fundamental science underlying drug action. This extension to the existing IUPHAR/British Pharmacological Society Guide to Pharmacology supports research into the development of drugs targeted at modulating immune, inflammatory or infectious components of disease. To provide a deeper context for how the resource can support research we show data in GtoImmuPdb relating to a case study on the targeting of vascular inflammation.