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P47: PAEDIATRIC OBSERVED FOOD CHALLENGES IN NEW ZEALAND: A CASE FOR DIVERSIFYING CARE
Author(s) -
Preece K,
Ang M,
Brothers S,
Craig A,
Sinclair J,
Smolnicki M,
Sutherland M,
Smiley R,
Townend T
Publication year - 2017
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.47_13578
Subject(s) - medicine , food allergy , anaphylaxis , oral food challenge , family medicine , pediatrics , tertiary care , prospective cohort study , gold standard (test) , health care , health professionals , allergy , environmental health , emergency medicine , surgery , economics , immunology , economic growth
Background: The clinical manifestations of mammalian meat allergy (MMA) are varied, encompassing urticaria, angioedema, gastrointestinal symptoms and anaphylaxis. Diagnosis is difficult based on clinical history alone as there are many differential diagnoses to exclude. Specific IgE (sIgE) to alpha-gal is considered a useful diagnostic test. Sensitisation to alpha-gal is considered a prerequisite to MMA. In Australia, one major mechanism is through tick bites from Ixodes holocyclus.