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Measurement of Glomerular Filtration Rate using a Single Injection of 51 Cr‐Edetic Acid
Author(s) -
Bailey R. R.,
Rogers T. G. H.,
Tait J. J.
Publication year - 1970
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1970.19.3.255
Subject(s) - renal function , urine , chemistry , clearance , creatinine , filtration (mathematics) , urine collection device , chromatography , urology , medicine , biochemistry , mathematics , statistics
Summary A simple method of estimating the glomerular filtration rate using a single injection of 51 Cr‐EDTA is described. The technique, which avoids urine collections, has been found to correlate well with the 24 hour endogenous creatinine clearance over a wide range of renal function. The complex is not attached to erythrocytes or significantly bound to plasma proteins. In non‐oedematous patients equilibration in the body space is completed in under 2 hours, following which an exponential fall in plasma activity occurs.