Measurement of Glomerular Filtration Rate using a Single Injection of  51 Cr‐Edetic Acid | Zendy

Bailey R. R. | Zendy; Rogers T. G. H. | Zendy; Tait J. J. | Zendy

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Measurement of Glomerular Filtration Rate using a Single Injection of 51 Cr‐Edetic Acid

Author(s) -

Bailey R. R.,

Rogers T. G. H.,

Tait J. J.

Publication year - 1970

Publication title -

australasian annals of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.596

H-Index - 70

eISSN - 1445-5994

pISSN - 0571-9283

DOI - 10.1111/imj.1970.19.3.255

Subject(s) - renal function , urine , chemistry , clearance , creatinine , filtration (mathematics) , urine collection device , chromatography , urology , medicine , biochemistry , mathematics , statistics

Summary A simple method of estimating the glomerular filtration rate using a single injection of 51 Cr‐EDTA is described. The technique, which avoids urine collections, has been found to correlate well with the 24 hour endogenous creatinine clearance over a wide range of renal function. The complex is not attached to erythrocytes or significantly bound to plasma proteins. In non‐oedematous patients equilibration in the body space is completed in under 2 hours, following which an exponential fall in plasma activity occurs.

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