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A Double Isotope Method to Measure Vitamin B 12 Absorption
Author(s) -
Campbell C. B.,
Craswell P. W.
Publication year - 1970
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1970.19.1.42
Subject(s) - absorption (acoustics) , excretion , isotope , chemistry , vitamin , chromatography , biochemistry , materials science , physics , quantum mechanics , composite material
Summary A double isotope method using 51 Cr chromic chloride as a non‐absorbable marker was used to study absorption of vitamin B 12 . Results were compared with those obtained by the Schilling test and, in some patients, the total faecal excretion method. The test proved reliable with certain advantages over other methods of assessing vitamin B 12 absorption. It measures absorption directly, does not require quantitative collection of excreta, is independent of renal function and results are available within forty‐eight hours.