Premium
THE PLACE OF PROPHYLACTIC ANTIBIOTIC IN PERITONEAL DIALYSIS
Author(s) -
EREMIN JENNIFER,
MARSHALL VER C.
Publication year - 1969
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1969.18.3.264
Subject(s) - peritoneal dialysis , medicine , antibiotics , ampicillin , dialysis , surgery , intensive care medicine , microbiology and biotechnology , biology
SUMMARY The use of prophylactic antibiotic in peritoneal dialysis fluid is still widely recommended. Over a 12‐month period, a trial was carried out in order to assess the necessity for the use of antibiotic, and, when infection occurred, to correlate bacterial sensitivity with the antibiotic used. Patients requiring peritoneal dialysis for acute or chronic renal failure, who were dialysed in the one nursing environment using standard techniques, were included in the trial. Ampicillin, in a concentration of 12 x 5 µg/ml, was added to the dialysate, or withheld, according to the patient's unit record number. A total of 248 dialyses were performed for 56 patients, the number per patient varying from one to 21. The incidence of peritoneal infection was found to be low whether or not antibiotic was used. The infecting organism was insensitive to ampicillin on each occasion. It was concluded that the use of prophylactic antibiotic in peritoneal dialysate is unnecessary, when present techniques are employed, and that the organisms involved are not sensitive to any safe, broad spectrum antibiotic.