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FIBRINOLYSIS AND OBESITY: THE EFFECT OF WEIGHT REDUCTION
Author(s) -
GRACE C. S.
Publication year - 1969
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1969.18.1.32
Subject(s) - fibrinolysis , medicine , endocrinology , fibrinogen , triglyceride , obesity , weight loss , cholesterol
SUMMARY In eight obese subjects the initially low level of fibrinolytic activity increased after significant weight reduction. Reduction to a normal weight resulted in normal fibrinolytic activity, which was maintained when an isocaloric diet was resumed. Subsequent weight gain in two subjects caused a return of fibrinolytic activity to its initially low level. Overall, the ultimate level of fibrinolysis achieved was closely related to the degree of obesity. The changes in fibrinolysis appeared to be unrelated to changes in plasma levels of fibrinogen, triglyceride, cholesterol, free fatty acids and glucose.