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SOME EFFECTS OF THE INTRAVENOUS ADMINISTRATION OF CALCIUM IN MAN
Author(s) -
SMALLWOOD R. A.
Publication year - 1967
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1967.16.2.126
Subject(s) - bradycardia , atropine , calcium , sinus bradycardia , medicine , blood pressure , anesthesia , heart rate , endocrinology
Summary Calcium was administered by intravenous infusion or injection into 19 subjects, in doses ranging from 180 to 864 mg. The effects observed were bradycardia and sinus arrhythmia, an increased pulse pressure, shortening of the Q‐T c interval with depression and inversion of T waves, and an increase in gastric secretion. Atropine prevented the development of the bradycardia, sinus arrhythmia and the increase in gastric secretion, but did not prevent the increase in pulse pressure. None of the changes occurring ran parallel with the serum calcium levels, and with the exception of the T ‐wave changes, which persisted after the serum calcium levels had returned to normal, they appeared to be related to the acute rise in serum calcium levels.