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THE NATURAL HISTORY OF CHILDREN SUFFERING FROM VENTRICULAR SEPTAL DEFECT AND PULMONARY HYPERTENSION
Author(s) -
FARRAR F.,
DUNLOP IAN C.
Publication year - 1965
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1965.14.2.130
Subject(s) - medicine , pulmonary hypertension , cardiac catheterization , cardiology , vascular resistance , natural history , hemodynamics
Summary In order to assess the progress of children suffering from ventricular septal defects, especially those with pulmonary hypertension, and to help to determine a time for operation, a number of such patients have had cardiac catheterization studies repeated some years after the original study. Each physiological study has been compared with corresponding clinical, radiographic and electrocardiographic findings. Twenty‐one such patients have been included in the study, 18 of whom had significant pulmonary hypertension at the time of the investigation. Cardiac catheterization was repeated usually with a view to determining operability, so that figures may favour the doubtful and therefore more severe group. Over the period of the study, seven of the 18 patients (39%) had a significant rise in pulmonary vascular resistance. The electrocardiogram is a useful, although not infallible, guide to the trend of the pulmonary resistance.