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A CASE OF PROTEIN‐LOSING ENTEROPATHY
Author(s) -
FREEMAN ZELMAN
Publication year - 1960
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1960.9.4.303
Subject(s) - medicine , ileitis , gastroenterology , laparotomy , prednisone , enteropathy , biopsy , albumin , hypoalbuminemia , surgery , disease , crohn's disease
Summary The case described is of a woman, aged 61 years, presenting with diarrhoea, fever and œdema associated with hypoproteinæmia. Biopsy of the intestine showed acute non‐specific ileitis, and biopsy of the liver showed severe fatty degeneration. Laparotomy revealed some vascular engorgement of the subserosal vessels in the lower ileal area. After the commencement of prednisone therapy, there was considerable improvement in the clinical features, the hypoproteinæmia and the histological appearances in the liver. In the state of remission, studies with radioactive labelled albumin showed a degradation rate of 0.46 gramme per day per kilogram, and studies with radio‐iodinated polyvinylpyrrolidone showed a fMcal loss of 2.9% in 96 hours. Both figures are twice to three times normal.