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THE RELATIONSHIP BETWEEN BLOOD FIBRINOLYTIC ACTIVITY, SERUM LIPOPROTEINS AND SERUM CHOLESTEROL IN ATHEROSCLEROTIC ARTERIAL DISEASE
Author(s) -
NESTEL P. J.
Publication year - 1960
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1960.9.3.234
Subject(s) - fibrinolysis , medicine , myocardial infarction , lipoprotein(a) , cholesterol , intermittent claudication , lipoprotein , blood lipids , cardiology , blood serum , endocrinology , claudication , vascular disease , arterial disease
Summary Blood fibrinolytic activity, serum beta‐alpha lipoprotein ratios and serum cholesterol levels have been compared in patients with myocardial infarction, and in patients with intermittent claudication. Fibrinolytic activity was significantly less in patients with intermittent claudication than in patients with myocardial infarction. Serum cholesterol levels and serum lipoprotein ratios were significantly higher in patients with intermittent claudication than in patients with myocardial infarction. The significance of these results is discussed. Coefficients relating fibrinolytic time to serum cholesterol level and serum beta‐alpha lipoprotein ratio were highly significant in patients with intermittent claudication, but not significant in patients with myocardial infarction. When the data from both groups were combined, the coefficients relating fibrinolytic time to serum lipoprotein ratios and to serum cholesterol levels were found to be highly significant. This suggested that the presence of a significant correlation between fibrinolysis and lipids depended on the inclusion of subjects whose fibrinolytic times and lipid levels were high.