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PRIMARY ALDOSTERONISM‐CONN'S SYNDROME
Author(s) -
SIMPSON F. O.,
BARNETT A.
Publication year - 1960
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1960.9.3.188
Subject(s) - spironolactone , primary aldosteronism , aldosterone , endocrinology , medicine , potassium , vasopressin , urine , chemistry , organic chemistry
Summary Electrolyte‐balance studies on a patient with primary aldosteronism are reported. An aldosterone antagonist, spironolactone (“ SC 9420 ”, “ Aldactone ”, Searle), was effective in promoting sodium excretion and, to some extent, potassium retention. Spironolactone had some effect also after removal of the tumour. Vasopressin caused an increase in urine flow in this case.