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RECOVERY OF RENAL FUNCTION AFTER ACUTE RENAL FAILURE
Author(s) -
EDWARDS K. D. G.
Publication year - 1959
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1959.8.3.195
Subject(s) - renal function , medicine , clearance , creatinine , urology , proteinuria , diuretic , kidney , surgery
Summary Renal function tests, including those of plasma creatinine level and endogenous creatinine clearance, were performed on 15 patients for periods of up to 76 weeks after the onset of recovery from acute renal failure. Hypertension was common in the first two weeks, and persisted in one patient. Proteinuria occurred commonly during the early diuretic phase, but disappeared in all except two cases. Microscopically evident hæmaturia and cylindruria were present in most cases initially and persisted in two. Renal tract infection during recovery was common, but was cleared up by appropriate antibacterial agents. Streptomycin was avoided, and the dosage of other agents was reduced in proportion to reduction in renal function. The glomerular filtration rate, measured as endogenous creatinine clearance, improved steadily during the first three to 12 weeks, and in all cases except one reached normal levels within 12 weeks. One patient had persistently impaired renal function.