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A FATAL CASE OF ACUTE PHOSPHORUS POISONING
Author(s) -
CRANE C. W.,
EBELING P.,
BENTLEY A. B.
Publication year - 1959
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1959.8.1.66
Subject(s) - aminoaciduria , urine , cystine , taurine , arginine , excretion , urinary system , chemistry , phosphorus , medicine , endocrinology , coma (optics) , amino acid , biochemistry , enzyme , organic chemistry , physics , cysteine , optics
SUMMARY A typical, fatal case of phosphorus poisoning is described. Examination of the urine over the final three days showed a progressive fall in the total nitrogen excretion, with grossly elevated values for a‐amino nitrogen. Plasma and urinary aminoacid chromatograms suggest that tubular damage was a factor in the production of the aminoaciduria. The urinary aminoacid patterns differed in several respects from those reported in other conditions causing hepatic coma. Cystine and taurine concentrations were low, while arginine and beta‐aminoisobutyric acid could not be detected. Arginine was detected only after hydrolysis of the urine.