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THE LEAD CONTENT OF BONE IN CHRONIC BRIGHT'S DISEASE
Author(s) -
HENDERSON D. A.,
INGLIS J. A.
Publication year - 1957
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1957.6.2.145
Subject(s) - medicine , lead poisoning , disease , chronic disease , pathological , pediatrics , psychiatry
SUMMARY Some cases of chronic Bright's disease in the twenty to forty‐nine years age group in Queensland can be ascribed by clinico‐pathological study to known cases, such as glomerulonephritis, chronic pyelonephritis and essential hypertension. By far the larger proportion, amounting to 63% in the present series, cannot be so allotted. The bone lead content of persons in those cases of known ætiology is the same as those of persons who died without chronic Bright's disease. The bone lead content of the persons in the group of unknown ætiology is significantly higher than in these two groups. The available evidence suggests that this high lead content is due, with few exceptions, to excessive absorption during childhood. Bone lead content can be used in cases of chronic Bright's disease as a valid indication of excessive lead absorption. Its estimation may provide a clue to the ætiology of some cases of chronic Bright's disease.