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PRIMARY SYSTEMIC AMYLOIDOSIS
Author(s) -
LAZARUS L.
Publication year - 1957
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1957.6.2.116
Subject(s) - amyloidosis , medicine , autopsy , primary systemic amyloidosis , nephrotic syndrome , heart failure , disease , systemic disease , pathology , cardiac amyloidosis , cardiology
SUMMARY A man aged forty‐seven years, with no previous history of cardiac disease, suddenly presented with congestive cardiac failure, an electrocardiogram suggestive of healed infarct and a nephrotic syndrome. Haemoptysis and hmatemesis indicated the involvement of other systems. He died suddenly in his sleep. Autopsy showed generalized amyloid infiltration and no primary cause of amyloidosis. The literature has been briefly reviewed. Primary systemic amyloidosis is a multisystemic disease with protean clinical manifestations. It should be considered in any patient with disease of more than one bodily system, and particularly should it be considered in any patient with cardiac failure of obscure ætiology.