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AUTOERYTHROCYTE SENSITIZATION WITH A CIRCULATING FIBRINOLYTIC FACTOR
Author(s) -
REED C. S. H.,
FIRKIN B. G.
Publication year - 1957
Publication title -
australasian annals of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 0571-9283
DOI - 10.1111/imj.1957.6.1.58
Subject(s) - sensitization , medicine , risk factor , factor v , factor xiii , surgery , immunology , fibrin , thrombosis
Summary A woman, aged forty years, had suffered painful spontaneous bruising from the time of the menarche at the age of fourteen years. Prior to this and subsequently she had suffered a number of episodes of severe bleeding, usually two or three days after minor surgery or confinement. At the time of study she had suffered an intracranial hemorrhage. Autoerythrocyte sensitization and also a circulating fibrinolytic factor were demonstrated. This factor was thought to be associated with her red cells. Infusion of human serum albumin was associated with subjective and objective improvement.