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Incidence and predictors of idiopathic pulmonary fibrosis complicating Type 2 diabetes: the Fremantle Diabetes Study Phase I
Author(s) -
Navaratnam Vidya,
Davis Timothy M. E.,
Hubbard Richard,
Davis Wendy A.
Publication year - 2021
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.15191
Subject(s) - medicine , diabetes mellitus , type 2 diabetes , incidence (geometry) , confidence interval , idiopathic pulmonary fibrosis , cohort , cohort study , endocrinology , lung , physics , optics
During 106 865 person‐years of follow up, 17 (1.3%) Fremantle Diabetes Study Phase I participants with Type 2 diabetes and 57 (1.1%) matched individuals without diabetes developed idiopathic pulmonary fibrosis (IPF), an incidence rate ratio (95% confidence interval) of 1.40 (0.76–2.44) ( P = 0.22). In the diabetes cohort, age at diabetes diagnosis and total serum cholesterol (inversely) predicted incident IPF in competing risk multivariable models. The incidence of IPF was low in community‐based cohorts, regardless of Type 2 diabetes status.