Premium
Specificity of serum amyloid A as a biomarker of idiopathic pulmonary fibrosis
Author(s) -
Vietri Lucia,
d'Alessandro Miriana,
Bergantini Laura,
Carleo Alfonso,
Cameli Paolo,
Mazzei Maria Antonietta,
Sestini Piersante,
Bargagli Elena
Publication year - 2020
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.15113
Subject(s) - medicine , serum amyloid a , idiopathic pulmonary fibrosis , biomarker , proinflammatory cytokine , serum amyloid a protein , interstitial lung disease , pulmonary fibrosis , amyloid (mycology) , pathology , immunology , fibrosis , gastroenterology , inflammation , lung , biochemistry , chemistry
Serum amyloid A (SAA) is an apo‐lipoprotein produced by the liver in response to proinflammatory cytokines. Few data are available on SAA levels in patients with idiopathic pulmonary fibrosis (IPF), the most common idiopathic form of interstitial pneumonitis (ILD). This study compared SAA concentration in IPF patients to other ILD groups to explore its potential use as a clinical biomarker.