Premium
Cancer‐associated prothrombotic pathways: leucocytosis, but not thrombocytosis, correlates with venous thromboembolism in women with ovarian cancer
Author(s) -
LópezSalazar Javier,
RamírezTirado Laura A.,
GómezContreras Nora,
PachecoBravo Irlanda,
Cortés Evelyn,
Gallardo Dolores,
Arrieta Oscar,
CesarmanMaus Gabriela
Publication year - 2020
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.14762
Subject(s) - thrombocytosis , medicine , ovarian cancer , thrombosis , cancer , venous thrombosis , venous thromboembolism , gastroenterology , platelet , oncology
Risk factors for venous thromboembolism in cancer vary between tumours. Leucocytosis, thrombocytosis, tumour histology and vascular compression may drive thrombosis in ovarian cancer. Thrombosis developed in 13.4% of our patients. Higher median leucocyte, neutrophil and monocyte counts were related to thrombosis. Thrombocytosis >350 × 10 9 /L was frequent (63.8%), but not predictive of thrombosis. Identification of prothrombotic biomarkers may help personalise preventive treatments.