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Hyponatraemia in heart failure
Author(s) -
Tee Su Ling,
Sindone Andrew,
Roger Simon,
Atherton John,
Amerena John,
D'Emden Michael,
Erlich Jonathan,
De Pasquale Carmine
Publication year - 2020
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.14624
Subject(s) - medicine , heart failure , intensive care medicine , pathophysiology , cardiology
Hyponatraemia is common in heart failure (HF). It is estimated that over 20% of patients admitted to hospital with HF have hyponatraemia. It has also been repeatedly shown to be a surrogate marker of increased morbidity and mortality in this specific population. This review focuses on the pathophysiology of hyponatraemia through the activation of neurohormonal cascades in HF, the clinical implications of sustained hyponatraemia and treatment options in the management of this challenging phenomenon.