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Gastrografin: a diagnostic and therapeutic agent
Author(s) -
Ekladious Adel,
Wheeler Luke P.,
Yamanaka Mai
Publication year - 2018
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.14125
Subject(s) - medicine , citation , library science , gold coast , unit (ring theory) , general hospital , family medicine , history , archaeology , computer science , psychology , mathematics education
Gastrografin is a water‐soluble, high osmolality contrast medium that has been used diagnostically to define, and therapeutically to relieve adhesive small bowel obstructions (SBO). Experimental and proof‐of‐concept studies have demonstrated that oral Gastrografin is both safe and effective at relieving up to 70% of adhesive SBO when administered in the first 24 h.1 This is primarily due to its hyper‐osmotic nature, as it promotes extra‐luminal fluid shift into the bowel lumen, decreasing oedema and improving peristaltic bowel action.2 When used effectively, Gastrografin may negate the need for surgical intervention where surgery is not possible, or not readily available.