Premium
Prevalence of restless legs syndrome in a tertiary cohort of ambulant patients with chronic liver disease
Author(s) -
Ma Michael X.,
Huang Yi,
Adams Leon A.,
Gilpin Robert,
Garas George,
MacQuillan Gerry,
Jeffrey Gary P.,
Nicholas Ross Mac
Publication year - 2018
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.13719
Subject(s) - medicine , restless legs syndrome , hepatic encephalopathy , odds ratio , chronic liver disease , cohort , cirrhosis , confidence interval , liver disease , pediatrics , gastroenterology , physical therapy , neurology , psychiatry
A cross‐sectional survey of 188 ambulant patients with chronic liver disease was performed to determine the prevalence of restless legs syndrome (RLS) using a validated patient completed questionnaire. Patient responses were verified by standardised telephone interview. RLS was identified in 64 (34%) patients. Significantly, more patients with cirrhosis had RLS than patients without RLS (43.9 vs 23.3%, P = 0.003, respectively). Cirrhotic patients with a history of hepatic encephalopathy were also more likely to have RLS than patients without hepatic encephalopathy (odds ratio = 4.33, 95% confidence interval = 1.40–13.37, P = 0.011). Patients with chronic liver disease may be at risk for RLS; early detection and treatment may improve patient outcomes.