High urinary interleukin‐8 levels is associated with poor prognosis in idiopathic membranous nephropathy | Zendy

Chen Jilin | Zendy; Fu Xiaoye | Zendy; Sun Yanling | Zendy; Zhang Shengkun | Zendy; Xie Hua | Zendy; Lin Hongli | Zendy

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High urinary interleukin‐8 levels is associated with poor prognosis in idiopathic membranous nephropathy

Author(s) -

Chen Jilin,

Fu Xiaoye,

Sun Yanling,

Zhang Shengkun,

Xie Hua,

Lin Hongli

Publication year - 2018

Publication title -

internal medicine journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.596

H-Index - 70

eISSN - 1445-5994

pISSN - 1444-0903

DOI - 10.1111/imj.13698

Subject(s) - medicine , membranous nephropathy , urinary system , interleukin , nephropathy , immunology , glomerulonephritis , endocrinology , kidney , cytokine , diabetes mellitus

Biomarkers required to assess accurately the prognosis of idiopathic membranous nephropathy (IMN) are still unavailable. A retrospective study on 156 IMN patients showed only urinary IL‐8 was associated with the achievement of initial complete remission (CR) in IMN patients. A urinary IL‐8 level of less than 61.25 pg/mL was more sensitive for prediction of CR in IMN patients. Therefore, urinary IL‐8 may be a potential biomarker for evaluating short‐term prognosis of IMN patients.

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