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Managing hyponatraemia secondary to primary polydipsia: beware too rapid correction of hyponatraemia
Author(s) -
Boehm Emma,
Kumar Shanal,
Nankervis Alison,
Colman Peter
Publication year - 2017
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.13507
Subject(s) - medicine , hyponatremia , desmopressin , polydipsia , diuresis , hypernatremia , thirst , sodium , water intoxication , fluid restriction , tonicity , intensive care medicine , pediatrics , endocrinology , diabetes mellitus , renal function , chemistry , organic chemistry
We describe three cases of severe hyponatraemia in the setting of primary polydipsia that were managed in our centre in 2016. Despite receiving different solute loads, large volume diuresis and rapid correction of serum sodium occurred in all cases. Given the potentially catastrophic consequence of osmotic demyelination, we highlight the judicious use of desmopressin and hypotonic fluid infusion to mitigate sodium overcorrection in this setting.