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Comprehensive dietary education in treated gout patients does not further improve serum urate
Author(s) -
Holland R.,
McGill N. W.
Publication year - 2015
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.12661
Subject(s) - medicine , gout , rheumatology , physical therapy , randomized controlled trial , uric acid , intervention (counseling) , psychiatry
Background/Aim This study aims to investigate the influence of dietary education in patients with gout on a stable dose of urate‐lowering therapy ( ULT ). Methods Males and females aged >18 years with a history of gout, receiving an appropriate and stable dose of ULT , were recruited from two tertiary hospitals and randomised into two groups. The control group received basic advice regarding the importance of compliance with therapy and the benefit of weight loss. The intervention group received comprehensive dietary advice based on the B ritish S ociety of R heumatology G uidelines. Both groups received education at baseline and 3 months. Serum urate was measured at baseline, 3 months and 6 months, and a questionnaire was completed at baseline and at 6 months. The primary outcome of the study was to compare the change in serum urate between groups. Results Thirty patients were recruited into the study. There was no difference in serum urate between the control and intervention group at 6 months (0.29 mmol/L vs 0.29 mmol/L at baseline and 0.27 mmol/L vs 0.30 mmol/L at 6 months). The intervention group showed a statistically significant improvement in knowledge (8/13 in control group at baseline to 9/13 at 6 months vs 8/13 in intervention group at baseline to 12/13 at 6 months, P < 0.05) and self‐reported dietary modification (1 in control vs 7 in intervention P < 0.05) at 6 months. Conclusion This randomised controlled trial shows that in patients on ULT , providing education on diet does not lead to any clinically significant difference in serum urate at 6 months.