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Testosterone deficiency and quality of life in A ustralasian testicular cancer survivors: a prospective cohort study
Author(s) -
O'Carrigan B.,
Fournier M.,
Olver I. N.,
Stockler M. R.,
Whitford H.,
Toner G. C.,
Thomson D. B.,
Davis I. D.,
Hanning F.,
Singhal N.,
Underhill C.,
Clingan P.,
McDonald A.,
Boland A.,
Grimison P.
Publication year - 2014
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.12500
Subject(s) - medicine , prospective cohort study , testosterone (patch) , quality of life (healthcare) , cohort , testosterone replacement , testicular cancer , cancer , cohort study , population , gynecology , hormone , pediatrics , endocrinology , androgen , nursing , environmental health
This is the first prospective study in a contemporary A ustralian/ N ew Z ealand population to determine the prevalence of testosterone deficiency in testicular cancer survivors at 12 months from treatment, and any association with poorer quality of life. Hormone assays from 54 evaluable patients in a prospective cohort study revealed biochemical hypogonadism in 18 patients (33%) and low‐normal testosterone in 13 patients (24%). We found no association between testosterone levels and quality of life (all P > 0.05). Hypogonadal patients should be considered for testosterone replacement to prevent long‐term morbidity.