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Eltrombopag for resistant immune thrombocytopenia secondary to chronic lymphocytic leukaemia
Author(s) -
Jolliffe E.,
Romeril K.
Publication year - 2014
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.12468
Subject(s) - eltrombopag , medicine , splenectomy , immune thrombocytopenia , chronic lymphocytic leukemia , immunology , immune system , agonist , platelet , receptor , leukemia , spleen
Autoimmune manifestations are a common occurrence with chronic lymphocytic leukaemia ( CLL ). We describe a case of CLL ‐associated immune thrombocytopenia ( ITP ) that had a loss of response to standard treatment for ITP . The thrombopoeitin receptor agonist, eltrombopag, was successfully used preoperatively to increase the platelet count to a safer level, in this instance to facilitate laparoscopic splenectomy.