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Rising cost of anticancer drugs in A ustralia
Author(s) -
Karikios D. J.,
Schofield D.,
Salkeld G.,
Mann K. P.,
Trotman J.,
Stockler M. R.
Publication year - 2014
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.12399
Subject(s) - medicine , medical prescription , anticancer drug , drug , drug prices , pharmacology , toxicology , public economics , economics , biology
Background Anticancer drugs are often expensive and are contributing to the growing cost of cancer care. Concerns have been raised about the effect rising costs may have on availability of new anticancer drugs. Aim This study aims to determine the recent changes in the costs of anticancer drugs in A ustralia. Methods Publicly available expenditure and prices paid by the A ustralian Pharmaceutical Benefits Scheme ( PBS ) for anticancer drugs from 2000 to 2012 were reviewed. The measures used to determine changes in cost were total PBS expenditure and average price paid by the PBS per prescription for anticancer drugs and for all PBS listed drugs. An estimated monthly price paid for newly listed anticancer drugs was also calculated. Results Annual PBS expenditure on anticancer drugs rose from A$65 million in 1999–2000 to A$466 million in 2011–2012; an average increase of 19% per annum. The average price paid by the PBS per anticancer drug prescription, adjusted for inflation, increased 133% from A$337 to A$786. The real average annual increase in the price per anticancer drug prescription was more than double that for all other PBS drugs combined (7.6% vs 2.8%, difference 4.8%, 95% confidence interval −0.4% to 10.1%, P = 0.07). The median price for a month's treatment of the new anticancer drugs listed was A$4919 (range A$1003 to A$12 578, 2012 prices). Conclusions PBS expenditure and the price of anticancer drugs in A ustralia rose substantially from 2000 to 2012. Dealing with these burgeoning costs will be a major challenge for our health system and for those affected by cancer.