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Intravenous thrombolysis is unsafe in stroke due to infective endocarditis
Author(s) -
Brownlee W. J.,
Anderson N. E.,
Barber P. A.
Publication year - 2014
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.12343
Subject(s) - medicine , thrombolysis , contraindication , infective endocarditis , stroke (engine) , endocarditis , occult , complication , embolism , acute stroke , surgery , tissue plasminogen activator , myocardial infarction , mechanical engineering , alternative medicine , pathology , engineering
Embolic stroke is the most common neurological complication of infective endocarditis and a major source of morbidity and mortality. Septic embolism is considered a contraindication to intravenous thrombolysis in patients with ischaemic stroke because of concerns over an increased risk of intracranial haemorrhage. We describe a patient with occult endocarditis who was treated with thrombolysis for acute stroke and review other cases reported in the literature.

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