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Leukaemias into the 21st century – part 2: the chronic leukaemias
Author(s) -
Gibson J.,
Iland H. J.,
Larsen S. R.,
Brown C. M. S.,
Joshua D. E.
Publication year - 2013
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.12135
Subject(s) - medicine , myeloid , chronic myeloid leukaemia , disease , immunology , lineage (genetic) , pathology , genetics , biology , gene
Like the acute leukaemias, the chronic leukaemias are broadly classified according to their cell lineage of origin. Chronic myeloid leukaemia and chronic lymphocytic leukaemia are the most common disease entities within the myeloid and lymphoid lineages, although several less common entities are well recognised within each broad subgroup. In common with the dramatic progress in the acute leukaemias, there has been considerable progress in our understanding of the biology and molecular genetics of the chronic leukaemias that is now being translated into significant therapeutic advances.