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Cardiac dysfunction and N ‐terminal pro‐ B ‐type natriuretic peptide in exacerbations of chronic obstructive pulmonary disease
Author(s) -
Lee M. H. S.,
Chang C. L.,
Davies A. R.,
Davis M.,
Hancox R. J.
Publication year - 2013
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1111/imj.12112
Subject(s) - medicine , natriuretic peptide , copd , pathophysiology , pulmonary disease , cardiology , heart failure , pulmonary hypertension , heart disease , disease
Elevated levels of B ‐type natriuretic peptides among patients with exacerbations of chronic obstructive pulmonary disease ( COPD ) are associated with higher mortality. The pathophysiology is unclear. To establish if elevated levels of N ‐terminal pro‐ B ‐type natriuretic peptide ( NT ‐ proBNP ) are due to right or left heart dysfunction, we performed echocardiograms in 18 patients admitted to hospital with COPD . Elevated levels of NT ‐ proBNP were associated with both right and left heart dysfunction and indicate that these patients have biventricular dysfunction rather than isolated right ventricular compromise.