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Epitope masking may limit antibody boosting to malaria vaccines
Author(s) -
Kurtovic Liriye,
Boyle Michelle J,
Beeson James G
Publication year - 2021
Publication title -
immunology and cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0818-9641
DOI - 10.1111/imcb.12415
Subject(s) - boosting (machine learning) , virology , malaria , epitope , limit (mathematics) , antibody , computational biology , computer science , immunology , biology , artificial intelligence , mathematics , mathematical analysis
We discuss the study by McNamara et al., who report that low levels of antigen‐specific antibodies in serum can limit the boosting of antibody and B‐cell responses following immunization with live attenuated malaria sporozoites.