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B cells on the brain: meningeal IgA and a novel gut–brain firewall
Author(s) -
Hepworth Matthew R,
Greenhalgh Andrew D,
Cook Peter C
Publication year - 2021
Publication title -
immunology and cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0818-9641
DOI - 10.1111/imcb.12412
Subject(s) - secretion , biology , immunoglobulin a , immunology , neuroscience , pathology , medicine , immune system , immunoglobulin g , endocrinology
Fitzpatrick et al . describe how IgA secretion by B cells and plasma cells in the mengines is crucial for protection against microbial invasion into the brain and the CNS.
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