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B cells: we need them now more than ever
Author(s) -
Deenick Elissa K
Publication year - 2020
Publication title -
immunology and cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0818-9641
DOI - 10.1111/imcb.12348
Subject(s) - immune system , immunology , immunity , humoral immunity , antibody , biology , component (thermodynamics) , feature (linguistics) , disease , b cell , medicine , philosophy , pathology , linguistics , physics , thermodynamics
The humoral immune response, that is, the production of antibodies by B cells, is a critical component of immunity to infection and underlies the protection provided by the majority of successful vaccines. This Special Feature explores some of the latest advances in understanding B cell activation and differentiation, as well as how these processes can go wrong in disease.