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Senescence blurs the line between innate and adaptive immune cells
Author(s) -
Quinn Kylie M,
Linterman Michelle A
Publication year - 2020
Publication title -
immunology and cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0818-9641
DOI - 10.1111/imcb.12341
Subject(s) - innate immune system , senescence , immune system , acquired immune system , biology , microbiology and biotechnology , cellular senescence , immunology , first line , innate lymphoid cell , medicine , genetics , gene , phenotype
In Covre et al. and Pereira et al ., the authors demonstrate the parallels between senescent NK cells and senescent CD8 T cells, and formalise the mechanism by which senescent CD8 T cells become more NK cell‐like, through the action of sestrins.