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Urtica dioica for treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia
Author(s) -
Hosseinabadi Reza,
Heidari Mohammad,
Anbari Khatereh,
Pournia Yadollah
Publication year - 2014
Publication title -
international journal of urological nursing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.184
H-Index - 8
eISSN - 1749-771X
pISSN - 1749-7701
DOI - 10.1111/ijun.12038
Subject(s) - urtica dioica , medicine , prostate specific antigen , hyperplasia , lower urinary tract symptoms , clinical trial , quality of life (healthcare) , population , prostate , urology , physiology , traditional medicine , nursing , cancer , environmental health
Benign prostatic hyperplasia ( BPH ) is a common problem of the elderly population. This study was conducted to investigate the effect of Urtica dioica on the clinical symptoms of BPH. This double‐blind clinical trial included 248 patients with symptomatic BPH in Shohada Ashayer Hospital of Khorramabad. The patients were randomly divided into four groups of treatment with U . dioica 3 g, U . dioica 5 g, U . dioica 7 g and treatment with prazosin 1 mg alone as the control group. The clinical symptoms, patients' quality of life and level of serum prostate‐specific antigen ( PSA ) were measured before and 2 months after the intervention. The results of the study showed significant differences between the four groups after the intervention for the scores of clinical symptoms and patients' quality of life, while no significant differences were found for serum PSA levels. Sheffe post hoc comparisons showed significant improvements in the scores of the patients' clinical symptom in the U . dioica 5 g/d and U . dioica 7 g/d groups. The results of the study showed that simultaneous consumption of higher doses of U . dioica , up to 7 g/d, plus prazosin, compared with the consumption of prazosin alone, resulted in significant improvements in the clinical symptoms of BPH.