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Benefits of robotic cystectomy compared with open cystectomy in an Enhanced Recovery After Surgery program: A propensity‐matched analysis
Author(s) -
Tan Yu Guang,
Allen John Carson,
Tay Kae Jack,
Huang Hong Hong,
Lee Lui Shiong
Publication year - 2020
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/iju.14300
Subject(s) - cystectomy , medicine , urinary diversion , perioperative , bladder cancer , surgery , propensity score matching , ileus , urology , urinary system , robotic surgery , cancer
Objectives To compare the perioperative and oncological outcomes between robot‐assisted radical cystectomy with intracorporeal urinary diversion versus open cystectomy for bladder cancer in a contemporary Enhanced Recovery After Surgery cohort. Methods All consecutive patients who underwent radical cystectomy and managed under an Enhanced Recovery After Surgery protocol, from December 2013 to October 2018, were reviewed. Propensity score adjustment was carried out to reduce biases attributable to covariate imbalances. Results There were 19 robot‐assisted radical cystectomy with intracorporeal urinary diversion and 21 open cystectomy patients. The robot‐assisted radical cystectomy with intracorporeal urinary diversion cohort was associated with lower estimated blood loss (397 vs 787 mL, P = 0.05), with a trend toward shorter duration of ileus and postoperative opioid administration. These benefits were apparent, despite a longer operative time (581 vs 446 mins, P = 0.03), a higher proportion of orthotopic bladder reconstruction (26.3 vs 9.5%, P = 0.08), a more prevalent use of neoadjuvant chemotherapy and a higher number of salvage cystectomies for the robot‐assisted radical cystectomy with intracorporeal urinary diversion group. Comparable perioperative complications and length of hospital stay were observed. The pathological and intermediate oncological outcomes were similar in both groups (locally advanced disease: 52.6 vs 47.6%, P = 0.85; lymph node yield: 29 vs 34, P = 0.23). The mean recurrence‐free survival and overall survival in the robot‐assisted radical cystectomy with intracorporeal urinary diversion group was 37.5 and 43.0 months, respectively, compared with 21.4 ( P = 0.09) and 35.5 ( P = 0.14) months, respectively, in open cystectomy. Conclusion Robot‐assisted radical cystectomy with intracorporeal urinary diversion has perioperative benefits of lower estimated blood loss, with a trend toward faster bowel recovery and a shorter duration of opioid analgesia when compared with open cystectomy. Robot‐assisted radical cystectomy with intracorporeal urinary diversion also achieves similar intermediate‐term oncological and survival outcomes.