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Umbilical closure using 2‐octyl cyanoacrylate in transumbilical laparoscopic adrenalectomy: A randomized controlled trial
Author(s) -
Fukumoto Keishiro,
Miyajima Akira,
Matsumoto Kazuhiro,
Kobayashi Hiroaki,
Niwa Naoya,
Hongo Hiroshi,
Kurihara Isao,
Kikuchi Eiji,
Oya Mototsugu
Publication year - 2020
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/iju.14270
Subject(s) - medicine , cyanoacrylate , glue , surgery , randomized controlled trial , adrenalectomy , adhesive , chemistry , materials science , organic chemistry , layer (electronics) , composite material
Objectives To evaluate postoperative pain and esthetic outcomes in patients undergoing transumbilical laparoscopic adrenalectomy with wound closure using 2‐octyl cyanoacrylate. Methods A total of 26 patients who underwent laparoscopic adrenalectomy with the transumbilical approach and agreed to participate in this study were included. Patients were randomly divided into two groups: the 2‐octyl cyanoacrylate group (Glue group) or the non‐use group (non‐Glue group). A single surgeon (AM) carried out all procedures between 2014 and 2017. Results There were no significant differences in the clinical background of the Glue and non‐Glue groups. The number of patients with moderate or high levels of pain in the resting/moving period on postoperative days 1, 2 and 3 was 6/10 (46%/77%), 6/9 (46%/69%) and 3/5 (23%/38%) in the non‐Glue group, and 5/7 (38%/54%), 2/7 (15%/54%) and 1/3 (8%/23%) in the Glue group. These differences were not significant. In the subgroup analysis of patients aged <50 years, the numbers were 4/6 (57%/86%), 5/7 (71%/100%) and 3/5 (43%/71%) in the non‐Glue group, and 3/4 (33%/44%), 1/4 (11%/44%) and 0/1 (0%/11%) in the Glue group in the resting/moving period. On postoperative days 2 and 3, these differences were significant ( P = 0.035 and 0.037 in the resting period, and P = 0.017 and 0.013 in the moving period). Conclusions 2‐octyl cyanoacrylate can be used safely for laparoscopic adrenalectomy with the transumbilical approach, and might be useful for reducing postoperative pain in patients aged <50 years.